AICAR for Sale — Lab-Tested AICAR at 99.0% HPLC Purity

AICAR 50mg research peptide vial from Amino Fuel Labs

AICAR is a ampk activator supplied by Amino Fuel Labs for laboratory research in ampk pathway research, endurance and exercise mimetic studies, glucose uptake and type 2 diabetes research. This listing covers a single lyophilized powder configuration, each released against a batch-specific third-party Certificate of Analysis reporting 99.4% purity by reversed-phase HPLC. Vials ship from our US facility with lot documentation matching the exact batch you receive. Research use only.

$60.00 — In stock, ships same business day

AICAR Research Overview

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), also called Acadesine, is a cell-permeable nucleoside that converts intracellularly to ZMP, a direct AMP-mimic. It is one of the original tool compounds used to study AMPK pharmacology.

Available AICAR Research Strengths

Purity and Laboratory Testing

Lot AFL-AICAR50-2026-001 (tested 2026-04-09) of AICAR was assayed by an independent laboratory using reversed-phase HPLC for purity and mass spectrometry for identity confirmation, returning 99.4% purity. The Certificate of Analysis shipped in the box matches the lot number printed on the vial.

Technical Product Information

Molecular formula C₉H₁₄N₄O₈P, molecular weight 338.21 g/mol. Once inside the cell, AICAR is phosphorylated to ZMP, which allosterically activates AMPK without altering the AMP/ATP ratio. AMPK activation increases glucose uptake, fatty acid oxidation, mitochondrial biogenesis and PGC-1α expression — earning AICAR the 'exercise in a pill' label in the 2008 Salk Institute paper. AICAR is supplied as lyophilized powder and is classified in our catalog under ampk activator for ampk activator work. Recorded research categories for this compound include ampk pathway research, endurance and exercise mimetic studies, glucose uptake and type 2 diabetes research, ischemia-reperfusion injury studies. Handling notes: store at -20°c (freezer), protect the vial from light, and avoid repeated freeze–thaw cycles once reconstituted. Amino Fuel Labs publishes no dosing protocol for AICAR: the compound is distributed for in-vitro and preclinical laboratory research only and is not intended for human or veterinary use.

Certificate of Analysis

View the AICAR Certificate of Analysis for the current lot, including HPLC purity and mass-spectrometry identity data.

Frequently Asked Questions

Is AICAR a peptide?

No. AICAR is a small-molecule nucleoside analog, not a peptide. It is grouped with peptide research because it targets the same AMPK pathways as MOTS-C, metformin and exercise.

What's the difference between AICAR and metformin?

Both activate AMPK but via different mechanisms. AICAR is a direct AMP-mimic. Metformin acts indirectly by inhibiting mitochondrial complex I. AICAR is more potent in vitro but has a much shorter half-life in vivo.

What purity is your AICAR?

≥99.4% HPLC purity with COA included on every batch.

What is AICAR studied for?

AICAR appears in laboratory research covering exercise mimetic research, diabetes studies, metabolic syndrome. All references describe in-vitro and preclinical study models only.

Does AICAR include a Certificate of Analysis?

Yes. Each AICAR lot ships with a batch-specific third-party Certificate of Analysis reporting 99.4% purity by reversed-phase HPLC alongside mass-spectrometry identity confirmation.

What form does AICAR arrive in?

AICAR is supplied as lyophilized powder in a sealed vial, packed with the lot documentation for the exact batch shipped.

Related Research Products

Research Use Only

AICAR is supplied strictly for laboratory research use. It is not a drug, food or cosmetic and is not intended for human or veterinary use, consumption, diagnosis, treatment or prevention of any condition. Amino Fuel Labs publishes no human dosing or administration guidance.

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