Melanocortin Receptor Research Peptides
Melanocortin analogues are studied for their interaction with the MC1R–MC5R receptor family in pigmentation and central nervous system research models. This hub groups the melanocortin-family compounds in the catalog with their lot documentation and technical data.
3 active compounds · $55.00–$55.00 per vial
Compounds in this category
Melanotan 1 10mg
Melanotan 1 (Afamelanotide, MT-1) is a synthetic linear analog of alpha-melanocyte-stimulating hormone (α-MSH). It stimulates melanin production in the skin through melanocortin receptor activation, providing photoprotective effects and research applications in skin pigmentation. Research dosing: 1mg subcutaneously every other day during loading, then weekly for maintenance.
- Strengths:
- 10mg
- Form:
- Lyophilized Powder
Melanotan 2 10mg
Melanotan 2 (MT-2) is a synthetic cyclic α-MSH analog with non-selective melanocortin receptor activity (MC1R-MC5R). A 2024 British Journal of Dermatology study analyzed user experiences and outcomes. Research confirms potent melanogenesis stimulation through MC1R activation, with additional effects on appetite regulation via MC4R and metabolic pathways. The cyclic structure provides enhanced receptor binding affinity compared to linear analogs. Research dosing: 250-500mcg subcutaneously daily during loading, then 2-3 times weekly for maintenance.
- Strengths:
- 10mg
- Form:
- Lyophilized Powder
PT-141 10mg
PT-141 (Bremelanotide) is an FDA-approved cyclic heptapeptide that activates melanocortin MC3R and MC4R receptors in the hypothalamus. Unlike PDE5 inhibitors, it works through central nervous system pathways rather than peripheral vasodilation. Clinical trials confirmed efficacy for hypoactive sexual desire disorder (HSDD) in premenopausal women, with onset of action within 30-45 minutes and duration of 6-12 hours without cardiovascular effects. Research dosing: 1.75mg subcutaneously as needed, 45 minutes before activity.
- Strengths:
- 10mg
- Form:
- Lyophilized Powder
Research references
Frequently asked questions
What distinguishes the melanocortin analogues listed here?
They differ in receptor selectivity and sequence. Each product page lists the molecular formula, weight and sequence recorded for that compound.
Is identity confirmed by mass spectrometry?
Yes, where the lot Certificate of Analysis reports it — the linked COA shows the method used for that lot.
Are these approved for human use?
No. They are supplied strictly for laboratory research and are not for human or veterinary use.
Other research categories
All products are supplied for laboratory research use only. Not for human or veterinary use, and not for diagnostic or therapeutic application.