Kisspeptin 10mg Research Peptide
Kisspeptin (also known as Metastin) is a neuropeptide encoded by the KISS1 gene. The 10-amino-acid C-terminal fragment, Kisspeptin-10, is the most potent endogenous activator of the GPR54 / KISS1R receptor on GnRH neurons in the hypothalamus, sitting at the very top of the reproductive hormone cascade.
Purity
99.4% HPLC-tested purity with COA support.
Size
10mg Lyophilized Powder.
Storage
-20°C (Freezer)
Research use
For laboratory research use only. Not for human or veterinary use.
Mechanism of action
Kisspeptin binds the KISS1R (GPR54) receptor on GnRH neurons, triggering pulsatile gonadotropin-releasing hormone secretion. This stimulates the anterior pituitary to release LH and FSH, which in turn drive endogenous testosterone production in males and estradiol/ovulation in females — without the suppressive feedback seen with exogenous hormones.
Research applications
- HPG axis and GnRH pulse-generator research
- Fertility, ovulation and puberty studies
- Hypogonadism and low-testosterone protocols
- PCOS and reproductive endocrinology research
- Non-suppressive endogenous hormone elevation studies
Frequently asked questions
What is Kisspeptin used for in research?
Kisspeptin is researched as the master upstream regulator of the HPG axis. It stimulates pulsatile GnRH release, which drives LH, FSH and downstream testosterone or estradiol — making it a key tool in fertility, puberty and hypogonadism studies.
How is Kisspeptin different from HCG?
HCG mimics LH at the testicular receptor and bypasses the brain. Kisspeptin acts upstream at the hypothalamus, recruiting the body's own GnRH-LH-FSH cascade — a more physiologic, non-suppressive research pathway.
Is your Kisspeptin third-party tested?
Yes. Every vial ships with HPLC and Mass Spec verification at ≥99.4% purity and an itemized batch-specific Certificate of Analysis.
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