KPV 10mg Research Peptide
KPV is a three-amino-acid C-terminal fragment of α-MSH (Lys-Pro-Val) that retains the anti-inflammatory activity of the parent peptide while losing the MC1R-mediated pigmentary effects. It penetrates cells without a dedicated receptor and concentrates intracellularly.
Purity
99.5% HPLC-tested purity with COA support.
Size
10mg Lyophilized Powder.
Storage
-20°C (Freezer)
Research use
For laboratory research use only. Not for human or veterinary use.
Mechanism of action
KPV downregulates NF-κB activation and reduces pro-inflammatory cytokine release (TNF-α, IL-1β, IL-6). In intestinal models it stabilizes tight junctions and restores barrier function — making it a leading research candidate for IBD, ulcerative colitis and gut-inflammation studies.
Research applications
- Inflammatory bowel disease (IBD) research
- Gut barrier integrity studies
- Topical anti-inflammatory research
- Wound healing studies
- Mast-cell modulation research
Frequently asked questions
How is KPV different from BPC-157?
Both are studied for gut health but via different mechanisms. BPC-157 promotes angiogenesis and tissue repair. KPV directly downregulates NF-κB-driven inflammation. The two are often paired in research stacks.
Why use KPV instead of full α-MSH?
KPV retains the anti-inflammatory activity of α-MSH without the MC1R-mediated pigmentation. Cleaner profile for inflammation research without melanocortin side effects.
Is KPV active orally?
Published preclinical work uses both injectable and oral administration. The compact tripeptide structure shows surprising oral bioavailability in intestinal models.
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