SS-31 10mg Research Peptide
SS-31 (D-Arg-2',6'-dimethyl-Tyr-Lys-Phe-NH₂), known clinically as Elamipretide and being developed by Stealth BioTherapeutics, is a synthetic Szeto-Schiller peptide that selectively concentrates in the inner mitochondrial membrane.
Purity
99.5% HPLC-tested purity with COA support.
Size
10mg Lyophilized Powder.
Storage
-20°C (Freezer)
Research use
For laboratory research use only. Not for human or veterinary use.
Mechanism of action
SS-31 binds cardiolipin, a phospholipid unique to the inner mitochondrial membrane. This stabilizes cristae architecture, reduces electron leak and improves electron transport chain efficiency. Clinical trials have explored its use in primary mitochondrial myopathy, Barth syndrome and age-related macular degeneration.
Research applications
- Mitochondrial dysfunction research
- Cardiolipin stabilization studies
- Heart failure and ischemia research
- Age-related mitochondrial decline studies
- Primary mitochondrial myopathy research
Frequently asked questions
Is SS-31 the same as Elamipretide?
Yes. SS-31 is the research name; Elamipretide is the clinical/development name used by Stealth BioTherapeutics. Same tetrapeptide sequence.
How does SS-31 differ from MOTS-C?
Both target mitochondria but differently. MOTS-C is a mitochondrial-encoded signaling peptide acting via AMPK. SS-31 is a synthetic peptide that physically binds cardiolipin on the inner mitochondrial membrane.
Has SS-31 been in human trials?
Yes. Phase II/III trials in primary mitochondrial myopathy, heart failure with reduced ejection fraction, Barth syndrome and dry AMD have been conducted by Stealth BioTherapeutics.
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