What Is SS-31?
SS-31 (also known as Elamipretide) is a synthetic tetrapeptide designed to target mitochondria — the powerhouses of the cell. It is one of the most researched peptides for improving cellular energy, reducing oxidative stress, and supporting organ health.
Researchers study SS-31 for heart conditions, kidney disease, mitochondrial disorders, eye health, and overall aging research.
How SS-31 Works
SS-31 enters cells and concentrates inside the mitochondria. It binds to cardiolipin (a key mitochondrial membrane lipid), protecting it from damage. This helps reduce harmful reactive oxygen species (ROS), improves energy production (ATP), and supports healthy mitochondrial function. Unlike many antioxidants, SS-31 works directly inside the mitochondria.
Key Research-Backed Benefits of SS-31
Improved Mitochondrial Function
Helps mitochondria produce energy more efficiently.
Reduced Oxidative Stress
Lowers damaging free radicals inside cells.
Heart Health Research
Studied for improving heart muscle function and reducing damage after heart events.
Kidney Protection
Shows promise in protecting kidneys from damage and improving function.
Anti-Aging Potential
Supports cellular energy that naturally declines with age.
Eye Health
Explored for conditions like dry age-related macular degeneration.
Muscle and Exercise Recovery
May help with muscle endurance and fatigue in research models.
SS-31 Research Dosage Protocols
Important: The following information is based on published research and is for laboratory and in vitro use only.
- General Research Dosing: 0.1–0.5 mg/kg per day, usually given by subcutaneous injection.
- Common Protocol: 10–40 mg daily (depending on study goals).
- Heart & Kidney Studies: Doses up to 40 mg per day have been used in clinical research.
- Administration: Subcutaneous injection is the most common method.
- Reconstitution: Mix with bacteriostatic water (example: 50 mg vial + 2 mL water = 25 mg/mL concentration). Store in the refrigerator.
- Cycle Length: Most studies run for 4–12 weeks, often with daily dosing.
Why Researchers Study SS-31
SS-31 is unique because it specifically targets and protects mitochondria. As mitochondrial dysfunction is linked to many age-related and chronic conditions, SS-31 is a valuable tool for energy metabolism, organ protection, and longevity research.
Important Research Notice: SS-31 is sold by Amino Fuel Labs strictly for laboratory research and in vitro use only. It is not FDA-approved for human consumption.
For researchers studying mitochondrial health, heart and kidney function, anti-aging, or cellular energy, we offer high-purity SS-31 with independent testing and fast domestic shipping.
Browse our full research peptide catalog including DSIP, Thymalin, HMG, VIP, HCG, Kisspeptin, Tesamorelin, Ipamorelin, NMN, BPC-157, TB-500, Retatrutide, and more.
Have questions about SS-31 research protocols or how it compares to other mitochondrial peptides? Leave a comment below — we're here to support the research community.
This article is for educational and research purposes only. SS-31 is sold for research use only and is not intended for human consumption.
