Research Comparison Reference
CJC-1295 vs Ipamorelin: Peptide Class and Pathway Comparison
A classification reference for two peptides that act on different receptor systems within growth-hormone research and are often studied together.
Attribute comparison
| Attribute | CJC-1295 (No DAC) | Ipamorelin |
|---|---|---|
| Compound class | GHRH analog | Pentapeptide secretagogue |
| Peptide or non-peptide | Peptide | Peptide |
| Amino-acid count | 29 (modified) | 5 |
| Receptor or pathway classification | GHRH receptor | Ghrelin / GHS receptor |
| Molecular weight | 3367.97 g/mol | 711.85 g/mol |
| Physical form | Lyophilized powder | Lyophilized powder |
| Laboratory research context | GHRH receptor signaling studies | GHS receptor signaling studies |
| Available from Amino Fuel Labs | Yes, as a blend with Ipamorelin | Yes, as part of the CJC-1295 / Ipamorelin blend |
Key structural differences
CJC-1295 without DAC is a modified analog of the first twenty-nine residues of growth hormone releasing hormone. It is classified as a GHRH receptor ligand and is roughly five times the mass of ipamorelin.
Ipamorelin is a synthetic pentapeptide classified as a growth hormone secretagogue acting at the ghrelin receptor. Five residues is a very short chain, and its molecular weight near 712 g/mol reflects that.
Because the two act at different receptors, they are not substitutes for one another in a study design. This is also why they appear together as a blend in catalog form rather than as alternatives.
Published research context
Both molecules have been investigated in preclinical models of growth-hormone axis signaling, and the GHRH analog class has additionally been studied in clinical settings for related molecules. Neither compound as supplied here is an approved drug product.
Frequently asked questions
- Do these two act on the same receptor?
- No. CJC-1295 is classified as a GHRH receptor ligand and ipamorelin as a ghrelin or growth hormone secretagogue receptor ligand.
- What does 'No DAC' refer to?
- It indicates the analog without the drug affinity complex modification that was designed to extend circulating presence through albumin binding.
- Is ipamorelin sold separately by Amino Fuel Labs?
- The current catalog lists ipamorelin as part of the CJC-1295 / Ipamorelin blend rather than as a standalone item.
- Are either approved for human use?
- No. Both are supplied as research material only and are not for human or veterinary use.
References
- PubMed — CJC-1295 and GHRH analog literature — National Library of Medicine
- PubMed — ipamorelin literature — National Library of Medicine
Related references
Research use only. The information in this library is educational and is not medical advice. Products are not intended to diagnose, treat, cure, or prevent disease and are not for human or veterinary consumption.